The domain within your query sequence starts at position 440 and ends at position 517; the E-value for the 2yu2 domain shown below is 1e-35.

DPQCSPKKDRQVHLTHFELEGLRCLVDKLESLPLHKKCVPTGIEDEDALIADVKILLEEL
ASSDPKLALTGVPIVQWP

This is a PDB domain - please see the PDBSUM entry of 2yu2 for further annotation